Application of Eudragit RS to Thermo-Sensitive Drug Delivery Systems. I. Thermo-Sensitive Drug Release from Acetaminophen Matrix Tablets Consisting of Eudragit RS/PEG 400 Blend Polymers.
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چکیده
منابع مشابه
Application of eudragit RS to thermo-sensitive drug delivery systems. I. Thermo-sensitive drug release from acetaminophen matrix tablets consisting of eudragit RS/PEG 400 blend polymers.
In order to develop the polymer materials having temperature-sensitive and high biological safety, Eudragit RS-PO and polyethylene glycol 400 (PEG 400) blend polymers (EPG) were prepared. The EPGs that have the glass transition temperature (Tg) at around the body temperature were prepared by the addition of 5--13% PEG 400 to Eudragit RS. As glassy polymers are not in thermodynamic equilibrium b...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2002
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.50.408